LA-3 Review

LA-3, by Live Cell Research, is a supplement which claims to help ward off stubborn belly fat while making you feel stronger and more healthy overall. Their secret is activation of  the enzyme AMPk, which orders the body to convert fat into energy rather than storing it. AMPk stands for adenosine monophosphate-activated protein kinase.

LA-3 body fatLive Cell Research is based out of Culver City, California. Their e-mail address is [email protected] and phone number is (844)-650-5933. They offer a 90-day money back guarantee on their products, no questions asked. Their main website is The website is generally informative in terms of the company’s vision and purpose, with a few other products listed to buy aside from LA-3.

LA-3 Facts

Because so much emphasis was placed onto the enzyme AMPk in the sales material for LA-3, I wanted to look further into it and get a better explanation of how it works in the body.

According to Better Nutrition, [1]

AMPk is found in every cell in the body and serves as a “master regulating switch” in energy metabolism. Overall, this enzyme plays a major role in determining our body fat composition. When we’re young, AMPk is more active, but as we age the cellular AMPk activation decreases, leading to fat accumulation and loss of muscle mass.  

The older you get, the less effective AMPk becomes in the body, causing weight gain over time. According to New Hope, “AMPk is more active, but as we age, the cellular AMPk activation decreases, leading to visceral fat accumulation and loss of muscle mass.” [4]

You can naturally boost AMPk levels in your body by exercising and reducing the number of calories you eat, or you can take a supplement that boosts AMPk levels in the body without exercise or caloric reduction.

LA-3 is such a supplement. The claim is it will help you with boosted energy, clearer thinking, decreased abdominal fat, and a stronger body overall. Each bottle of the LA-3 supplement contains a 30-day supply of the capsules, taken 2 per day with or without food. One bottle costs around $50.00 with shipping.

LA-3 weight loss supplementLA-3 Ingredients

Berberine, Quercetin, and Gynostemma (also known as Jiaogulan). Other Ingredients are Rice flour, hypromellose, and vegetable stearic acid. [2]

What’s The Word?

Any website is going to talk about how great their supplement is for health and weight loss. But what do purchasing customers say about this supplement?

LA-3 supplements can currently only be found on Live Cell Research’s main website. There were not many testimonials—positive or negative—on the site regarding the effectiveness of this particular brand of supplement. Nor is there a place to leave reviews on the product page.

But what is the word about AMPk itself, how it truly affects the body, its potential in regard to weight loss, and all the recent hype about it? According to the National Center for Biotechnology Information (NCBI),

AMP-activated protein kinase (AMPK) is a phylogenetic ally conserved fuel-sensing enzyme that is present in all mammalian cells. During exercise, it is activated in skeletal muscle in humans, and at least in rodents, also in adipose tissue, liver and perhaps other organs by events that increase the AMP/ATP ratio. [3]

The fact that AMPk enzymes can affect the levels of fat storage in the body makes this enzyme worth looking into. While there have been proven studies on AMPk being responsible for weight loss and weight gain, not many studies have been done on people taking LA-3.

What Does LA-3 Offer?

LA-3 offers the customer a supplement claiming to stimulate an enzyme that helps with the reduction of fat storage in the body. While there have been studies done on the enzyme AMPk itself which support this claim, whether or not LA-3 specifically works in your body is another story entirely. The company does provide a research tab to their findings, which is better than some companies offering similar products, but the research is relevant to their other products, not LA-3. They offer a weight loss supplement, but do not offer nutritional or exercise programs to go along with the supplement.

shutterstock_271586141The lack of support and customer voices regarding LA-3 does not lend consumer faith in purchasing. They do have a Facebook page,  but it was unhelpful in terms of both research verification and customer reviews. The overall concept and outside research on AMPk is believable, but the lack of support for LA-3 specifically makes it questionable.

  • Supported Enzyme Research
  • Transparent with ingredient list
  • Expensive
  • Lack of Testimonials

Is LA-3 Worth A Try?

Problematic. LA-3 is not cheap at almost $50.00 (discounted; regularly almost $90) for a month’s supply, and a purchase will be made solely on your faith in the marketing.

They do offer a 90-day money back guarantee. From the LA-3 product page, “You can return your order for any reason. We will gladly refund your money, no questions asked.”  But you will have to go through the hassle of contacting the company, shipping back the product, and then waiting for your refund.

While transparent with their ingredient list, there are no side effects mentioned on the company website, though the individual ingredients can be searched elsewhere online for possible side effects.

Overall, it is going to take more than a supplement to see weight loss, and the idea of exercise and clean eating is not mentioned on the Live Cell Research site.


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