Isagenix is famous for marketing health and wellness products pointed specifically toward weight loss. Their 30-Day Cleansing and Fat Burning System is one of the more popular packages offered. This is meant to help the dieter jump-start their weight loss with a 30-day cleanse.
Isagenix is a multi-level marketing (MLM) company aiming to create pyramids of success—aka money—by getting people to buy their products and sign up to sell them. They have a heavy digital footprint with social media; no in-home parties or door-to-door catalogs, but websites and Facebook and email for their distributors to hawk the wares.
The 30-Day Cleansing and Fat Burning System is basically a maxed-out version of the 9-Day Deep Cleanse System we reviewed here. Though it does seem to be a better value: the 9-Day System runs just over $200, while the 30-Day system—three times as long—runs just over $375. So let’s check it out.
How Does the Isagenix 30-Day Cleansing and Fat Burning System Work?
Your 30-Day Cleansing and Fat Burning System starter pack includes:
- 4 tubs of IsaLean Shakes (meal replacement; per serving, 24 g protein and 8 g fiber, 240 calories)
- 1 bottle of Ionix Supreme (liquid dietary supplement “primes the body and protects against stress” )
- 2 tubs Cleanse For Life (an antioxidant powder you mix with water)
- 1 bottle of Isagenix Snacks (antacid-sized chewable protein tablets for hunger pangs—your distributor will undoubtedly try to sell you extra-purchase snack bars or whey thins along with the starter pack)
- 1 bottle of the Natural Accelerator (thermogenic fat burner—“stimulant free” claim, but contains green tea extract, aka caffeine)
- 4 Hydrate Sticks (electrolyte-vitamin powdered drink)
- 1 bottle of IsaFlush (digestive aid that “encourages regularity”) 
- 1 Instructional System Guide
These products get mixed and matched between “Cleanse Days” and “Shake Days.” Basically fasting and less-than-fasting days. Cleanse Days are to be done only after 2-5 Shake Days.
What Does a Shake Day vs. a Cleanse Day Entail?
You will start off with a Shake Day:
- Replace breakfast and dinner with IsaLean Shakes. (240 calories each)
- Drink a glass of the Ionix Supreme supplement after your breakfast shake to help boost your clarity and focus.
- Take the Accelerator supplement with any meal to boost your metabolism.
- Make a 400- to 600-calorie lunch where half your plate should be vegetables and the other half is split between healthy grains and some sort of protein.
- The snacks are available if you need them, but they are more designed for Cleanse Days.
- At bedtime take the IsaFlush supplement to help support your digestive system.
You repeat Shake Day for 2-5 days total (it’s about 1000 calories a day unless you opt for the extra snack bars/thins). Then you do a Cleanse Day:
- Instead of a shake for breakfast, you’ll have 1 serving of the Cleanse For Life supplement (20 calories)
- At mid-morning, you have 1 serving of Cleanse for Life (20 calories)
- At mid-afternoon, you have one serving of Cleanse for Life (20 calories)
- In the evening, you have one serving of Cleanse for Life (20 calories)
- You are allowed 6 Isagenix snacks per day throughout the Cleanse Day, in case your blood sugar needs a boost (you think?)
- You drink lots of water, using the Hydrate sticks in some servings to make sure your body is replenished with proper electrolytes and nutrients.
- At bedtime take 1-2 IsaFlush capsules to ensure a healthy digestive system.
Repeat this schedule over the course of a month. Isagenix does NOT recommend doing more than 2 Cleanse Days in 1 week. Considering a Cleanse Day is eighty calories, I can imagine why. 
Is the Isagenix 30-Day Cleansing and Fat Burning System Safe?
As mentioned in the 9-Day Deep Cleanse review, ultra-low-calorie diets are always risky; medical professionals recommend going no lower than 1000 to 1200 calories unless you’re under strict doctor supervision. But if you take the maximum Isagenix recommends—a 600-calorie lunch on Shake Days, and a Cleanse Day only after five Shake Days—the risk is as minimized as this system allows. You’ll probably be hungry but not ready to eat your walking shoes.
Also, any kind of strenuous exercise on Cleanse Days is probably a bad idea—though apparently some distributors recommend it. If you’re consuming that small an amount of calories, you’re going to burn through them in the first half hour you’re out of bed.
What Kind of Ingredients Does Isagenix Use?
Isagenix ingredients are mostly whey, herbal extracts, and a few chemical-sounding substances that are there either for texture or anti-caking properties. So it certainly seems safe enough. Herbal extracts often don’t have a lot of research behind them, so it’s a good idea to check the labels before you consider buying Isagenix products. Then check with your doctor to see what concerns they may have with various ingredients. Isagenix does offer dairy-free and kosher versions of their shake mixes.
WARNING: The Cleanse for Life supplement contains ashwagandha root:
Ashwagandha could potentially induce spontaneous abortion of the fetus, according to the Memorial Sloan-Kettering Cancer Center. 
Do not take this if you’re trying to get pregnant right away (one assumes you’re not going to do any cleanse if you’re already pregnant).
Pros and Cons of 30-Day Cleansing and Fat Burning System
Gearing up to do a cleanse of any kind takes both desire and discipline. If you’re using a cleanse to jump-start a healthier way of eating and plan to ease back into real food—fresh produce, whole grains, lean proteins—it sets your mind into a new frame. At the very least, real food is going to be intensely welcome once you finish the cleanse. So that’s good.
And people have lost weight with this system. But one Amazon.com (third-party seller) review came with a hefty reality check:
Again here is the truth – if you alter your diet in a significant way, especially from a high protein/low carb perspective, you will see large losses – regardless of what you do (isagenix, macro counting, meal planning, paleo, atkins, etc). The first month your body will have a huge loss then it will level off as your body adjusts to the caloric change. Invariably regardless of the diet used the person will plateau as the body get used to the changes.
Isagenix can be very helpful to ppl who feel overwhelmed by making huge diet/lifestyle changes. It gives them rules to follow and a schedule to follow. And sometimes this is the start that a person needs to affirm their commitment to a healthy lifestyle change! Everyone wants to win, and succeed! However I believe it should be a goal on anyone that uses isagenix to transition smoothly off of it, which requires learning about nutrition and meal planning while you are doing the isagenix program.  (emphasis added)
The Truth About Isagenix
Now, let’s just call out the truth: Isagenix programs are quite nearly extortionate in cost. At least the 9-Day (which actually lasts eleven) plan tells you to expect up to seven pounds of weight loss for the $210 you pay—the 30-Day system doesn’t name a number at all. So let’s do the math: variables aside, if you can expect up to seven pounds gone in eleven days, it comes out to about nineteen pounds in thirty days. For almost $400.
Let that sink in: almost four hundred dollars for nineteen pounds. Maximum.
The Bottom Line
Like the 9-Day Deep Cleanse System, Isagenix’s 30-Day Cleansing and Fat Burning System offers very little results for the money you pay. Green salads with lean proteins and whole grains, water instead of soda, and apple slices instead of potato chips, over the course of a month. This will yield the same results for a fraction of the price. Add in a good multi-vitamin just for safe measure.
But if you need the discipline of “I paid half a mortgage payment for this, I’d best do it,” more power to you. Isagenix is not the worst program out there, and it’s certainly lower in caffeine than many I’ve reviewed. Just be smart about it and stick with those maximum recommendations.
Top 5 Diets in 2018*
6 Month MBG
|#1 PS1000 Plan||$$|
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*Individual results will vary.
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